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Clinical Studies

Our ingredients are clinically proven to be effective. We only use the highest quality ingredients when developing our products, following the most current scientific research.

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Date Published



Full Study



December, 2009

(An Anti-aging Hexapeptide)

INYLINE™ is a new hexapeptide developed by Lipotec that has been specifically designed using the molecular modelling technique. As biological activity is dependent on three-dimensional placement of specific functional groups or domains, molecular modelling allows designing this type of structures and simulate its behaviour in the space. INYLINE™ was designed according to the predicted structure of agrin's binding domain of MuSK's tyrosine kinase domain by molecular modelling.

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Ultra 15% Vitamin C

December, 2008

(An Anti-aging Tetrapeptide)

Lipotec has developed a new tetrapeptide obtained from a focused peptide library, specifically identified to fight the detrimental effects of UV radiation in human skin. PREVENTHELIA™ is a peptide born from preventive cosmetics: it acts by scavenging RCS and preventing skin from photoaging.

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Ultra 15% Vitamin C


Hyaluronic Acid
(Sodium Hyaluronate)

A high molecular mass substance belonging to the group of glycosaminoglycans and having a relative molecular mass of 0.4-3 million g/mol. Hyaluronic acid occurs as a physiological constituent of the intercellular ground substance of connective tissue, in the vitreous body of the eye and in synovial fluid.

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Pentapharm LTD



B5 Hydration,

Pure Hydration

July, 2005

(An Anti-aging Peptide)

The anti wrinkle octapeptide SNAP-8 is an elongation of the famous hexapeptide ARGIRELINE®. The study of the basic biochemical mechanisms of anti-wrinkle activity led to the revolutionary hexapeptide which has taken the cosmetic world by storm. Those same studies have now been applied to bring another addition to the Botulinum Toxin-inspired family of peptides.

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7.5% Eye Gel



Tens'Up™ is an innovative active ingredient with a marked lifting or tightening effect. It combines its lifting action with anti-aging activity as it increases collagen synthesis, so there is a dual action of immediate improvement in skin appearance and anti-aging treatment in the longer term. 

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Pivotal Group

Neck Fimring Serum

March 28, 2002

UGL Complex™
(Algae Extract)

Improves cell renewal and increased production of hyaluronic acid and collagen.

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Barnet Products

Repair Complex


(Caprooyl Tetrapeptide-3)

A peptide derived from growth factors that activates skin's natural repair function.

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Atrium Innovations

Refine Hydrator

April, 2007


Derived from organically farmed oats, Osilift® adheres to the skin to form a continuous and cohesive lifting film. Clinical studies showed skin firming within two hours after application and an anti-wrinkle effect after 28 days of twice daily applications.

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Line Smoother

February, 2007

(L-Teprenone Canitine)

Significantly improves the surface of the skin by creating with less dehydration and improved barrier function.

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Refine Hydrator

April, 2005

(Ascophyllum Nodosum Extract)

Stimulates cellular renewal to encourage the elimination of melanin by means of migration towards the strateum corneum.

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Codif Recherche et Nature

Triple Action Serum

March, 2011


 Hexapeptide that increases fatty tissue volume in specific areas improving facial appearance and providing attractive body curves. adifyline™ stimulates Peroxisome proliferator-activated receptor Gamma Coactivator 1α (PGC-1α) expression, enhancing adipogenesis rate. This leads to a higher lipid accumulation and volume growth in the desired areas like breast and cheeks.

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Volumizing Breast Cream

August, 2011

VoluPlus TM  

Voluplus™ is a natural active ingredient which is proven to increase the density of adipose tissue, causing a significant and noticeable volumizing effect. This cosmetic product contains a natural active ingredient from nutmeg (Macelignan) solubilized in macadamia oil. It increases breast volume and improves femine curves, acting naturally and safely on cells which retain corporal fat, leading to a superior breast development.

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Provital Group

Volumizing Breast Cream

July, 2003

Sepiwhite TM  MSH

New lightening acting through a novel mode of action. An alpha-MSH (melanotropin) antagonist, it reduces the synthesis of melanin pigments effectively while maintaining skin integrity. Its powder form is ideally suited to the form of cosmetic powders.

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Daily Polishing Cleanser

April 12th, 2010

New Study Evaluates Effectiveness of Vitamins for the Treatment of Sun-Damaged Skin

A recent study titled "Vitamins and photoaging: Do scientific data support their use?" advocates the usage of vitamins in oral and topical formulations. Published in the Journal of the American Academy of Dermatology, dermatologist Jenny Kim, M.D., Ph.D., FAAD, associate professor in the division of dermatology, at the University of California, Los Angeles (UCLA), and David Geffen School of Medicine in Los Angeles demonstrated the significant role of vitamins A, C, E, and B3 in photoaging skin. This study represents the role of key ingredients and their benefits to the skin. glotherapeutics contains these key ingredients in multiple formulations.The chart to the right illustrates the ingredients researched, the products that contain these ingredients and the product descriptions.


American Academy of Dermatology

View Chart for full product listing

April 2010


Gladback™ is an active ingredient for mature skin and/or for skin suffering the consequences of aging as well as for women close to menopause or post menopause.  It reduces the most visible effects of these processes on the skin, as it increases skin thickness, luminosity and microcirculation while decreasing the appearance of wrinkles caused by aging.

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Pivotal Group

Neck Firming Serum

Skin Firming Cream



A skin lightening study on 80 Chinese descent women demonstrated that an emulsion containing Alpha - Arbutinresulted in a faster and more pronounced skin lightening effect after 1 month when compared with other commonly used single components.

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Neck Firming Serum

Vitamin C Professional Mask



MELANOSTATINE®5 blocks the melanogenesis pathway and inhibits tyrosinase production and melanin synthesis.

MELANOSTATINE®5 is a biomimetic peptide antagonist specific of the α-MSH (α-Melanocyte-Stimulating Hormone). As an antagonist, MELANOSTATINE®5 competes against the natural ligand (α-MSH) on its specific receptor (MC1-R) by preventing any further activation of the tyrosinase, and thus blocking melanin synthesis Tyrosinase inhibition reduces the formation of unwanted pigmentation allowing for the control over skin tone and

brown spots.

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Atrium Biotechnologies

Vitamin C Professional Mask



SYN®-HYCAN helps to fight sagging skin by boosting hyaluronan content and increasing the expression of decorin and lumican.


SYN®-HYCAN boosts the production of skin identical hyaluronan by a factor of four (in vitro) and is able to increase the production of the important proteoglycans decorin (+73%) and lumican (+66%). A double-blind study in parallel groups was performed with 40 female volunteers, age 55–65, with visible skin sagging A formulation with or without 2.5% SYN®-HYCAN was applied twice daily on face and forearms. SYN®-HYCAN significantly increased tension (3%), tonicity (17%) and firmness (7%) of the skin compared to D0.

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Neck Firming Serum